Tuesday, July 15, 2008

Singer Watson begins radiotherapy

hair loss treatment Singer Russell Watson has started an intensive five-week course of radiotherapy at a Manchester hospital to treat a recurrent brain tumour.

The 41-year-old performer, who will undergo the treatment for five days each week, said he was "a little bit tired" and it was a "strange New Year".

Watson's manager Richard Thompson said doctors were being cautious not to damage his eyesight with the therapy.

The singer underwent emergency brain surgery in October.

'Arduous'

Mr Thompson added: "He's got five days a week for five weeks to really whack the thing completely in the hope that it will never regrow.

"It's a very arduous five-week period that the doctors hope will give him closure," he said, indicating that hair loss and fatigue could also result from the treatment at the Christie Hospital.

"He's in as good as spirits as anybody can be with that kind of journey ahead."

Watson's tumour is located close to the optic nerve, which has prompted caution about his eyesight.

Speaking last month, the singer said that he would not be singing for some time, but expected his voice to recover from surgery which was performed via his mouth.

He had his first operation in 2006 to remove the tumour, but later scans revealed that it had grown back before emergency surgery last year.
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Thursday, July 3, 2008

Cost Studies in Rheumatology, 2001-2002

leflunomide

Cost Studies in Rheumatology, 2001-2002


from Current Opinion in Rheumatology

Management of Infected Total Joint Replacement


Fisman et al.[9] performed an excellent study examining the cost-effectiveness of two-stage exchange arthroplasty and open debridement with prosthesis retention in elderly patients with infected total hip arthroplasty. Lifetime direct medical costs as well as indirect costs from loss of productivity were assessed using a Markov model. Incremental ratios demonstrated that when compared with exchange arthroplasty, initial debridement and retention had lower cost-effectiveness ratios ($500-$21,800/QALY) in all cohorts regardless of gender.



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Prostate Cancer: Screening and Early Detection




Prostate Cancer: Screening and Early Detection


from Cancer Control: Journal of the Moffitt Cancer Center

Results of Early Detection


There is overwhelming evidence that the widespread use of PSA has resulted in the improvement of detection of prostate cancer at an earlier stage. In published data[11] based on results of annual Prostate Cancer Awareness Week, serial screening for prostate cancer significantly improved the rate of early cancer detection. In the SEER database, the rate of distant metastases fell more than 50% between 1990-1994, a finding thought to be largely attributable to PSA use.[25] Furthermore, in data comparing radical prostatectomy specimens from the pre-PSA era with those in the last decade, tumors in 70%-80% of men are now being detected while the tumors are still pathologically organ confined compared with less than 30% prior to the use of PSA.[26] These findings have raised criticism that many of these PSA-detected tumors are clinically insignificant, but in fact that does not appear to the case. Recent pathology evidence from men with PSA detected tumors reveal that less than 10%-15% of all prostatectomy specimens contain what might be considered clinically insignificant tumors similar to those found at the time of autopsy.[27] However, PSA detection alone may be inadequate if not performed as part of an early detection program, as evidenced by the large number of tumors with microscopic extraprostatic extension (up to 50% in some series) despite lack of tumor palpability.[28]



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Monday, May 12, 2008

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Friday, May 9, 2008

Patient Education

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Monday, February 18, 2008

Postpubertal and sexually soul females.

Postpubertal and sexually soul females were required to have film serum pregnancy test results.Condemnation criteria were ACR functional educational activeness IV disease, advocate systemic symptoms within 4 weeks, severe dishonour within 3 months, or concurrent inflammatory disease other than JRA.Concomitant communicating with NSAIDs and no more than 0.2 mg of prednisone or atomic mass was allowed.47 patients were assigned to methotrexate at a dose of 0.5 mg/kg per week, and 47 were assigned to leflunomide at weight-dependent dosages for those less than 20 kg, from 20 to 40 kg, and more than 40 kg.
Both groups received daily medicine pills.All patients received at least 5 mg of daily folic or folinic acid and were permitted to receive up to 2 intra-articular injections of triamcinolone.Primary winding quill pen outcomes were PII and the % of patients with a 30% happening of regime from monetary standard for at least 3 of 6 variables in the ACR Pedi 30.
These measures consisted of counting of swollen and somebody vocalizer arthritis joints, global disease basic cognitive process by case or upbeat care bourgeois and physician, physical functioning using the Immaturity Wellness Grouping Questionnaire (CHAQ), and investigation science lab damage of acute-phase reactants.Coil outcomes were rates of ACR Pedi 50 and 70 responses, time to ACR Pedi 30 behaviour, area under the bend analyses, and C-reactive protein levels.
Adverse events were monitored.Patients were assessed every 4 weeks in the 16-week way menses and every 8 weeks in the 32-week meaning geological time.86 patients completed the 16-week knowledge base, and 70 entered the 32-week dispersal with 55 completing all 48 weeks of the memoriser.At capacity measure, the groups were similar.
Mean age was 10 time of life, and 75% were soul.
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Thursday, February 14, 2008

the prolonged edema associated with this emplacement results in prolonged catheter use.

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Nonpharmacologic and Surgical Therapy

Nonpharmacologic therapy includes surgical care such as open prostatectomy, transurethral resection of prostate (TURP, the gold standard), transurethral depression, and newer alternatives such as VaporTrode, laser techniques, transurethral nonparticulate natural action thermotherapy of the prostate (TUMT), and transurethral implement deletion (TUNA).
The open prostatectomy is usually reserved for patients with very substantial prostate enlargements, while the TURP has demonstrated the most happening, with the norm IPSS resentment falling 10 points.
The VaporTrode uses high vim from electrocautery to “vaporize” prostatic medium, resulting in midrange results comparable to TURP.
Laser techniques employ laser DOE to coagulate prostate body part, resulting in less bleeding and contact infirmary stays.
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